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咗他莫司 Zotarolimus

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产品信息

产品名称：咗他莫司 Zotarolimus	纯度：99% min
CAS NO：221877-54-9	溶解度：DMSO: ≥ 33 mg/mL
分子式：C₅₂H₇₉N₅O₁₂	包装：可按客户要求包装
分子量：966.21	贮存：-20℃

质量控制

备注说明

Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.

咗他莫司Zotarolimus 是雷帕霉素类似物。

物化属性:

密度：1.25

沸点：1016.2°Cat760mmHg

闪光点：568.4°C

PSA：218.80000

LOGP：5.98540

参考文献

[1]. Wagner R et al. Rapamycin analogs with reduced systemic exposure. et al. Bioorg Med Chem Lett. 2005 Dec 1, 15(23), 5340-3.