0576-88813233
E7046是prostaglandin E2 (PGE2) receptor EP4的选择性抑制剂,IC50为13.5 nM,Ki为23.14 nM
[1]. X. Bao, et al. Combination of a Novel EP4 Antagonist E7046 and Radiation Therapy Promotes Anti-tumor Immune Response and Tumor Rejection in Preclinical Tumor Models. International Journal of Radiation Oncology Biology Physics
[2]. Diana I. Albu, et al. EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity. OncoImmunology.
版权所有 Copyright(C) 2018-2024 台州市科瑞生物技术有限公司