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盐酸氨柔比星Amrubicin (hydrochloride) (SM-5887 (hydrochloride)) 是一种 DNA 拓扑异构酶 II (topoisomerase II) 抑制剂,可用于癌症研究。
物化属性:
熔点:145-151°
沸点:717.8°C at 760 mmHg
闪光点:387.9°C
PSA:176.61000
LOGP:2.13410
[1]. Hayashi S, et al. Enhancement of radiosensitivity by topoisomerase II inhibitor, amrubicin and amrubicinol, in human lung adenocarcinoma A549 cells and kinetics of apoptosis and necrosis induction. Int J Mol Med. 2006 Nov;18(5):909-15.
[2]. Hanada M, et al. Amrubicin, a novel 9-aminoanthracycline, enhances the antitumor activity of chemotherapeutic agents against human cancer cells in vitro and in vivo. Cancer Sci. 2007 Mar;98(3):447-54.
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