0576-88813233
SB 242084盐酸盐是5-HT2C选择性抑制剂,pKi值9.0,对5-HT2A和5-HT2B作用弱100倍以上。
[1]. Kennett GA, et al. SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology. 1997 Apr-May;36(4-5):609-20.
[2]. Bromidge SM, et al. 6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]- indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist. J Med Chem. 1997 Oct 24;40(22):3494-6.
版权所有 Copyright(C) 2018-2024 台州市科瑞生物技术有限公司